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CONTROLLED PREVENTION – How to do it ?

Let me go back to the significance of this image from the recent scientific findings that we published in collaboration with Concordia University (Lutchman and al, 2016). The term ‘’CONTROLLED PREVENTION’’ comes from the recipient of a large number of scientific awards, DNA repair specialist and member of the Academy of Sciences, Miroslav Radman (the […]

Let me go back to the significance of this image from the recent scientific findings that we published in collaboration with Concordia University (Lutchman and al, 2016).

The term ‘’CONTROLLED PREVENTION’’ comes from the recipient of a large number of scientific awards, DNA repair specialist and member of the Academy of Sciences, Miroslav Radman (the link of it’s video, in french):

Controlled prevention as an anti-ageing solution!

How is this possible? We already know that approaches which specifically address a single mechanism of action have minimal impact on primary ageing. For instance, taking antioxidants, such as Vitamin E or C, is not as effective as directly stimulating cells’ natural antioxidant mechanisms. A recent discovery describes this option as being the key to delaying ageing and illness:

The recommended key option is to globally improve all antioxidant enzymes and to stimulate all of our natural antioxidant mechanisms. What remains to be developed are new medications or nutritional supplements based on this principle which, initially, plays a part in increasing levels of NADPH.

I believe this is part of the answer. Species that live longer, compared to other similar animals, usually have a much higher resistance to cell oxidation, but also, repair and maintenance mechanisms that remain active much longer. This includes DNA repair, damaged proteins, the recycling of cell components (autophagy), etc.

If we add into this the retention of healthy mitochondria (our body’s energy plants at the heart of the ageing process and many illnesses), we achieve healthy ageing. In this way, by increasing our resistance to ageing and by keeping our mitochondria healthy, a great number of age-related diseases can be prevented (reduced incidence).

Therefore, the objective is to discover the molecules which enable the continued functionality of all of the maintenance and repair mechanisms, the stimulation of our antioxidant cellular defences, and the retention of healthy mitochondria.

Thus, the figure shows the impact of our discoveries on ten cellular factors affecting lifespan. These effects are far greater than those of resveratrol or rapamycin, which represent the best results observed until now. We have, of course, filed patents for this significant finding.

This represents new hope, while much research is still to be done before confirming these results in humans. Moreover, proper nutrition, regular exercise, good stress and anxiety management, and an active social life will be necessary to maximize the effects.

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